Prenatal environmental exposures, epigenetics, and disease
نویسندگان
چکیده
منابع مشابه
Prenatal environmental exposures, epigenetics, and disease.
This review summarizes recent evidence that prenatal exposure to diverse environmental chemicals dysregulates the fetal epigenome, with potential consequences for subsequent developmental disorders and disease manifesting in childhood, over the lifecourse, or even transgenerationally. The primordial germ cells, embryo, and fetus are highly susceptible to epigenetic dysregulation by environmenta...
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It is becoming increasingly apparent that genetic factors are inadequate to fully explain many processes that shape development and disease. For example, monozygotic twin pairs, despite sharing identical DNA sequences, are often discordant for many traits and diseases, indicating that the same genotype can give rise to distinct phenotypes. This points towards the involvement of additional facto...
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ژورنال
عنوان ژورنال: Reproductive Toxicology
سال: 2011
ISSN: 0890-6238
DOI: 10.1016/j.reprotox.2010.12.055